Immune system cells called macrophages, which combat glycation. The only apparent drawback to this defiance system is that it is not complete and levels of AGE’s increase steadily with age. One reason is that kidney function tends to decline with advance age; another is that macrophages becomes less active, thus having a knock on effect with the skin immune system. Once AGE’s form they can directly induce the linking of collagen, even in the absence of glucose and oxidation (free radical) reactions.
Carnosine: Anti-glycation. The natural dipeptide carnosine may be another answer to the ageing process, especially glycation. Glucose is an example of a carbohydrate which is commonly encountered. It is also known as blood sugar and dextrose.
Visual analysis and consultation of skin:
1. Small pillows about the eye fold area around the mouth, neck, cheeks and chin.
2. Fine vertical crepe lines eyelids, neck, upper lip and decollete. Always seen with the loss of collagens structural integrity is a client over 45 years of age, so will have thin skin density and slow wound healing, may scar easily.
3. Dark maroon around the eyes and under black light.
4. Loss of resiliency and adhesion, seen as horizontal lines around the eyes, mandible under the chin, neck, decollete and loosening at the nasolabial folds. Could have excess keratinisation/comedones across the cheeks or mandible